Trump, Clinton score major victories

By Stephen Collinson, CNN

Washington (CNN)Donald Trump and Hillary Clinton scored huge victories Tuesday that bring them closer to a monumental duel for the White House in the fall.

Trump's political strength was on display with a clean sweep of races in Maryland, Delaware, Pennsylvania, Connecticut and Rhode Island. Clinton delivered big wins in Maryland and Pennsylvania -- the biggest prizes of the night -- along with Delaware and Connecticut. Bernie Sanders picked up his sole victory of the night in Rhode Island.

The wins for Trump -- following a massive victory last week in New York -- move him significantly closer to the 1,237 delegates he needs to win the nomination outright heading into the convention in July. In the process, he inflicted serious blows on the legitimacy of claims by rivals Texas Sen. Ted Cruz and Ohio Gov. John Kasich that he should be deprived of the nomination.

"This to me was our biggest night," Trump said in his victory speech. "I consider myself the presumptive nominee."

Clinton's big wins, meanwhile, help bolster her campaign's argument that it is time for Sanders to make a decision to stop personal and political attacks on the former secretary of state that could weaken her ahead of a showdown in November with Republicans.

She climbed on stage to cheers in her election night headquarters in Philadelphia, the city that will host the Democratic National Convention this summer.

"With your help, we are going to come back to Philadelphia for the Democratic National Convention with the most votes and the most pledged delegates," Clinton declared. "And we will unify our party to win this election and build an America where we can all rise together, an America where we lift each other up instead of tearing each other down."

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Clinton foreshadowed the potential general election clash with Trump that could center on women voters.

"The other day, Mr. Trump accused me, of playing the, quote, woman card," she said. "Well, if fighting for women's health care and paid family leave and equal pay is playing the woman card, then deal me in."

Trump struck back during his victory speech.

"I think the only card she has is the women's card," Trump said. "She has got nothing else going. Frankly, if Hillary Clinton were a man, I don't think she would get 5% of the vote."

He added: "And the beautiful thing is women don't like her, ok?"

As of 10:45 p.m. ET, Trump picked up at least 99 delegates on Tuesday, bringing him to 945 compared to Cruz at 563 and Kasich at 152. Clinton won at least 72 delegates, boosting her total to 2,026, which includes pledged and superdelegates. Sanders holds 1291, including pledged and superdelegates.

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Not backing down

Still, Trump and Clinton's challengers showed no sign of backing down Tuesday despite a rapidly narrowing path to the nomination.

Cruz, speaking before polls closed -- in a clear sign that he expected a bad night -- slammed the media for what he said was a premature judgment that the general-election nominees would be Clinton and Trump. He branded them "New York liberals."

But he predicted things would change next week.

"I've got good news for you tonight, this campaign moves back to more favorable terrain," Cruz told a crowd in Indiana.

Sanders also spoke early in West Virginia, which holds its primary next month, and made clear he is not leaving the race. He said he had a "significantly larger" lead in match-up polls over Trump than Clinton — hinting that he would press on with his bid to convince superdelegates to back him instead of Clinton at the Democratic National Convention in July.

He said he was winning independent voters and some Republicans and added: "That is a point that I hope the delegates to the Democratic convention fully understand."

Clinton banking on a big night

In the Democratic race, Clinton's victories build on her resounding success in New York, which stunted Sanders' momentum and left the senator -- for all his fundraising muscle and large rallies -- fending off calls from Clinton supporters to fold his campaign so that she can start exclusively targeting Republicans.

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Sanders and Clinton were competing for 384 pledged delegates on Tuesday. Clinton went into the night leading Sanders by 253 pledged delegates, according to a CNN estimate, and dominated the count among superdelegates -- party officials and activists who also have a convention vote.

At her victory speech, Clinton extended an olive branch to Sanders in an apparent effort to begin the process of unifying the Democratic Party behind her candidacy.

"I applaud Sen. Sanders and his millions of supporters for challenging us to get unaccountable money out of politics and putting greater emphasis to closing the gap of inequality," she said. "I know together we will get that done."

CNN's Dan Merica contributed to this report